Diagnosis and differential diagnosis of airway-centered interstitial fibrosis / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 99-102, 2005.
Article
em Zh
| WPRIM
| ID: wpr-343759
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To describe a form of interstitial lung disease pathologically characterized by small airway-centered interstitial fibrosis (ACIF).</p><p><b>METHODS</b>We analyzed the clinical, pulmonary functional, radiographic, and histologic characteristics of one ACIF case in Peking Union Medical College Hospital and reviewed 12 cases in literatures.</p><p><b>RESULTS</b>Clinically, patients presented with chronic cough and progressive dyspnea. Pulmonary function tests showed restrictive ventilatory pattern. Bronchoalveolar lavage showed a mild increase in lymphocytes in most cases. Chest radiography revealed diffuse reticulonodular infiltrates, with thickening of the bronchial walls and surrounding fibrosis. The key finding in histopathology was a distinctive pattern of ACIF centered on membranous and respiratory bronchioles.</p><p><b>CONCLUSIONS</b>ACIF is a disease that do not fit into any known category of interstitial lung disease. Whether it is a unique disease remains to be determined.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Patologia
/
Fibrose Pulmonar
/
Testes de Função Respiratória
/
Biópsia
/
Brônquios
/
Diagnóstico por Imagem
/
Tomografia Computadorizada por Raios X
/
Diagnóstico
/
Diagnóstico Diferencial
/
Pulmão
Tipo de estudo:
Diagnostic_studies
Limite:
Adult
/
Humans
/
Male
Idioma:
Zh
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2005
Tipo de documento:
Article