Surgical management of brain-stem gliomas: a retrospective analysis of 311 cases / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 7-12, 2005.
Article
em Zh
| WPRIM
| ID: wpr-343777
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To further study the clinical features, diagnosis, and surgery outcome of brain-stem gliomas.</p><p><b>METHODS</b>Totally 311 patients with brain-stem gliomas received surgery operations in our hospital from 1980 to the end of 2001. The clinical data, neuroimages, growth patterns, and operative feasibility were analyzed.</p><p><b>RESULTS</b>Different brain-stem gliomas showed different growth patterns. In this series, total excision rate of the tumor was 40.5%, subtotal 29.9%, partial 29.6%, and operative mortality 1.3%. Among 311 patients, 72.4% patients had been improved and stable in their symptoms after operation, and 27.6% deteriorated or having transitory new signs. Five years survival rate is 67% in ependymoma patients, 42% in astrocytoma patients. None of brain-stem glioblastoma patients survived up to 5 years.</p><p><b>CONCLUSIONS</b>The histology and growth pattern of brainstem gliomas varies. The patients with well-differentiated gliomas of brain-stem may be cured by microsurgical removal. For malignant ones, partial removal may prolong survival and facilitate the following combined therapy.</p>
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Índice:
WPRIM
Assunto principal:
Astrocitoma
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Cirurgia Geral
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Mesencéfalo
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Ponte
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Imageamento por Ressonância Magnética
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Taxa de Sobrevida
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Estudos Retrospectivos
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Seguimentos
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Mortalidade
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Glioblastoma
Tipo de estudo:
Diagnostic_studies
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Observational_studies
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Prognostic_studies
Limite:
Adolescent
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Adult
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Aged
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Child
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Child, preschool
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Female
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Humans
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Infant
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Male
Idioma:
Zh
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2005
Tipo de documento:
Article