Treatment of acute radiation pneumonia with Qingfei Huatan Quyu method / 中国中西医结合杂志
Chinese Journal of Integrated Traditional and Western Medicine
;
(12): 414-417, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-343964
ABSTRACT
<p><b>OBJECTIVE</b>To observe the therapeutic effect of Qingfei Huatan Quyu method (QHQ, a Chinese medicinal therapy for clearing Fei-heat and dissolving phlegm-stasis) combined with hormone-antibiotic therapy (HAT) on radiation pneumonia (RP).</p><p><b>METHODS</b>Eighty-one patients with RP were randomized into two groups, 41 patients in the control group and 40 in the treatment group were treated with HAT alone and HAT combined with QHQ respectively for 21 days. The severity of RP was evaluated before and after treatment according to the criteria of the radiation therapy oncology group. The effect on TCM symptoms and chest roentgenogram, as well as on plasma levels of interleukin-6 ( IL-6) and transform growth factor-beta (TGF-beta) were detected.</p><p><b>RESULTS</b>After treatment, number of patients with RP graded as 0, 1, 2, 3, and 4 in the treatment group was 23, 10, 4, 2, and 1, respectively, while in the control group, 14, 9, 11, 4, and 3, respectively. The combined therapy showed effects in improving RP grading (P <0.01) and TCM syndromes were superior to those of HAT respectively (P < 0.05). Besides, levels of IL-6 and TGF-beta were lowered after treatment in the treatment group, showing a significant difference to those in the control group (P <0.05).</p><p><b>CONCLUSION</b>QHQ combined with HAT has a definite therapeutic effect on RP. It could efficiently decrease the plasma levels of IL-6 and TGF-beta in patients with RP.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Sangue
/
Medicamentos de Ervas Chinesas
/
Fator de Crescimento Transformador beta
/
Interleucina-6
/
Pneumonite por Radiação
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
Quimioterapia Combinada
/
Medicina Tradicional Chinesa
/
Antibacterianos
Tipo de estudo:
Ensaio Clínico Controlado
/
Estudo diagnóstico
Limite:
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Integrated Traditional and Western Medicine
Ano de publicação:
2008
Tipo de documento:
Artigo
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