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Research progress of neuraminidase inhibitors for anti-influenza / 药学学报
Acta Pharmaceutica Sinica ; (12): 935-942, 2009.
Artigo em Chinês | WPRIM | ID: wpr-344015
ABSTRACT
Influenza is a global contagious disease, which causes hundreds of thousands of people deaths. And new subtype of influenza may cause pandemic influenza, and lead to more serious consequence. Drugs for anti-influenza have played very important roles in influenza treatment and prevention, especially neuraminidase inhibitors are effective on both influenza A and B which have more safety and tolerance, therefore they have been widely used for influenza treatment. However, several viral drug-resistant cases have been reported. In this paper, the clinic therapy, prevention and drug resistance of neuraminidase inhibitors, including zanamivir, oseltamivir and peramivir, and progress in the research and development in our country are presented in order to promote research and development of new drugs for influenza treatment and prevention.
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Antivirais / Farmacologia / Virologia / Farmacorresistência Viral / Usos Terapêuticos / Tratamento Farmacológico / Inibidores Enzimáticos / Influenza Humana / Oseltamivir / Zanamivir Limite: Humanos Idioma: Chinês Revista: Acta Pharmaceutica Sinica Ano de publicação: 2009 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Antivirais / Farmacologia / Virologia / Farmacorresistência Viral / Usos Terapêuticos / Tratamento Farmacológico / Inibidores Enzimáticos / Influenza Humana / Oseltamivir / Zanamivir Limite: Humanos Idioma: Chinês Revista: Acta Pharmaceutica Sinica Ano de publicação: 2009 Tipo de documento: Artigo