Risk factors for capillary leak syndrome in children with tetralogy after operation / 浙江大学学报·医学版

ABSTRACT

<p><b>OBJECTIVE</b>To determine risk factors of capillary leak syndrome(CLS) in children with tetralogy after operation.</p><p><b>METHODS</b>Clinical data were retrospectively collected and analyzed from 32 tetralogy cases with CLS and 50 cases without CLS(control group), who received operation under cardiopulmonary bypass (CBP) in our hospital from October 2002 to December 2006. Risk factors with statistical significance were screened with univariate logistic regression analysis, independent risk factors of CLS were determined with multivariate logistic regression analysis. Postoperative outcome was compared between CLS group and control group.</p><p><b>RESULT</b>Logistic analysis showed that the risk factors for CLS were age(OR=6.783), duration of CBP(OR=4.756)and MGoon index (OR=3.826). There were statistical differences in injection of colloid, time of inotropic drugs and ventilation between CLS and control groups(P<0.01). Eight CLS cases underwent peritoneal dialysis and 2 CLS cases died.</p><p><b>CONCLUSION</b>The risk factors of CLS in children with tetralogy after CBP are age, duration of CBP and MGoon index.</p>