Relationship between measurements of tidal volume and thoracic inflating volume by pressure plethysmography in mice / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 257-260, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-344340
ABSTRACT
<p><b>OBJECTIVE</b>To evaluate the accordance of tidal volume (TV) with thoracic inflating volume (TIV) measured by pressure whole-body or double-chamber plethysmography in mice.</p><p><b>METHODS</b>TV and TIV by double-chamber plethysmography were simultaneously measured in 6 mice with spontaneous respiratory frequencies 90 - 120/min; TV and TIV by whole-body plethysmography were measured in 8 paralyzed mice ventilated by fixed frequency.</p><p><b>RESULT</b>TIV value by double-chamber plethysmography was significantly higher than TV [(0.369 +/- 0.014) ml vs (0.356 +/- 0.012) ml, P < 0.01)] in 6 spontaneously breathing mice. TIV value by whole-body plethysmography was significantly lower than TV[(0.233 +/- 0.003) ml vs 0.3 ml, P < 0.001] in 8 paralyzed mice.</p><p><b>CONCLUSION</b>The TV value assessed by TIV measurement can not be accurate, because of the humidifying and heating of inhaled air and negative thoracic pressure during the measurement.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pletismografia Total
/
Testes de Função Respiratória
/
Tórax
/
Volume de Ventilação Pulmonar
/
Camundongos Endogâmicos BALB C
Limite:
Animais
Idioma:
Chinês
Revista:
Journal of Zhejiang University. Medical sciences
Ano de publicação:
2008
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS