Alternatively spliced variants of constitutive androstane receptor in liver of mouse / 浙江大学学报·医学版
Journal of Zhejiang University. Medical sciences
;
(6): 113-117, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-344366
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the existence of alternatively spliced variants of constitutive androstane receptor (CAR) in liver of mouse.</p><p><b>METHODS</b>The nucleotide from liver of mouse was purified and the CAR cDNA was amplified by PCR. The fragments of CAR cDNA were cloned to T vector and sequence analysis was performed.</p><p><b>RESULT</b>Various spliced variants of CAR in liver mouse were confirmed by DNA sequencing.</p><p><b>CONCLUSION</b>There are alternatively spliced variants in CAR, which are located in the ligand binding sequence of CAR.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Dados de Sequência Molecular
/
Sequência de Aminoácidos
/
Processamento Alternativo
/
Receptores Citoplasmáticos e Nucleares
/
DNA Complementar
/
Sítios de Splice de RNA
/
Genética
/
Fígado
/
Metabolismo
Limite:
Animais
Idioma:
Chinês
Revista:
Journal of Zhejiang University. Medical sciences
Ano de publicação:
2008
Tipo de documento:
Artigo
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