Chemical constituents of fresh celery / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To study the chemical constituents of the whole plant of fresh celery (Apium graveolens).</p><p><b>METHOD</b>The constituents were isolated and purified by silica gel, Sephadex LH-20, ODS column chromatography, PTLC, HPLC, and their structures were elucidated on the basis of spectral evidences.</p><p><b>RESULT</b>Twenty compounds were obtained and identified as falcariondiol (1), (9Z) 1,9-heptadecadiene-4,6-diyne-3,8,11-triol (2), oplopandiol (3), bergapten (4), 5,8-dimethoxy psoralen (5), isofraxidin (6), eugenic acid (7), trans-ferulic acid (8), trans-cinnamic acid (9), p-hydroxyphenylethanol ferulate (10), caffeoylquinic acid (11), 5-p-trans-coumaroylquinic acid (12), sedanolide (13), lunularin (14), lunularic acid (15), 2-(3-methoxy-4-hydroxyphenol)-propane-1,3-diol (16), D-allitol (17), beta-sitosterol (18), benzolic acid (19), succinic acid (20).</p><p><b>CONCLUSION</b>Compounds 2, 3, 6, 10, 12, 14-17 were isolated from genus Apium for the first time.</p>