Application of biomarker CTX- II in osteoarthritis / 中国骨伤
China Journal of Orthopaedics and Traumatology
;
(12): 260-263, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-344744
ABSTRACT
Effective biomarkers for clinical usage of osteoarthritis are still limited. It was confirmed that C-terminal crosslinking telopeptide of type I collagen (CTX- II) was a specific marker reflecting degradation of articular cartilage. Detection of CTX- II could promptly reflect level of cartilage injury and degradation ,diagnose OA,predict its progress,monitor effects of drug treatment, thus, reflect the condition of osteoarthritis patient indirectly. Application of CTX- II focused mainly on in the early stage of OA and need together to detect with other biomarkers,in order to more accurately reflection of the pathological changes of OA,but the specific clinical significance of CTX- II results still need to improve further.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Osteoartrite
/
Patologia
/
Fragmentos de Peptídeos
/
Biomarcadores
/
Cartilagem Articular
/
Colágeno Tipo II
/
Diagnóstico Precoce
/
Diagnóstico
Tipo de estudo:
Estudo diagnóstico
/
Estudo prognóstico
/
Estudo de rastreamento
Limite:
Humanos
Idioma:
Chinês
Revista:
China Journal of Orthopaedics and Traumatology
Ano de publicação:
2013
Tipo de documento:
Artigo
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