Evaluation of the minimal invasiveness of laparoscopic operation for colorectal carcinoma / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 404-406, 2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-345169
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the minimal invasiveness of laparoscopic operation for colorectal carcinoma.</p><p><b>METHODS</b>Forty cases with pathologically proven colorectal carcinoma were divided into laparoscopic group (n=20) and open surgical group (n=20). Perioperative alterations of peripheral blood IL-6, IL-8, TNF-alpha, CRP, sICAM-1 and WBC CD11b were compared between the two groups. TNF-alpha, IL- 6, IL- 8 and sICAM-1 were determined by ELISA, CRP by scattered radiation turbidity comparison and WBC CD11b by flow cytometry with monoclonal antibody PS- CD11b, M2Ab.</p><p><b>RESULTS</b>The postoperative cytokine levels of TNF-alpha, IL-6 and IL-8 in open surgery group were significantly higher than those in laparoscopic group (P< 0.05). Dynamic level of sICAM-1 at 6 and 24 hours after operation in open surgery group were significantly higher than those in laparoscopic group. Peripheral WBC CD11b decreased to the lowest level at 6 hours after operation in open surgery group,significantly lower than that in laparoscopic group (P< 0.05).</p><p><b>CONCLUSION</b>Laparoscopic surgery for colorectal carcinoma exerts less effects on patients than traditional open surgery, and can maintain patients defense function,therefore it is less invasive.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Período Pós-Operatório
/
Cirurgia Geral
/
Sangue
/
Proteína C-Reativa
/
Neoplasias Colorretais
/
Interleucina-8
/
Interleucina-6
/
Fator de Necrose Tumoral alfa
/
Laparoscopia
Limite:
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Gastrointestinal Surgery
Ano de publicação:
2005
Tipo de documento:
Artigo
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