Analysis of the clinicopathological features of Chinese hereditary nonpolyposis colorectal cancer / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
;
(12): 316-318, 2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-345184
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the clinicopathological features of Chinese hereditary nonpolyposis colorectal cancer (HNPCC).</p><p><b>METHODS</b>Patients who met the Amsterdam criteria were enrolled in this study from several hospitals in China. Clinicopathological features of patients with HNPCC were compared between the patients with suspected HNPCC and sporadic colorectal cancer.</p><p><b>RESULTS</b>One hundred and sixty-seven individuals from 31 families met the Amsterdam criteria. The average age was 48.6 (22-78) years old. There were 43 cases (31.9%) with ascending colon cancer and 52 cases (38.5%) with rectal cancer. The 3-, 5-, 10- years survival rate was 70.3%, 49.9% and 39.7% respectively. The incidence of multiple primary neoplasms was 20.4% .</p><p><b>CONCLUSIONS</b>Chinese HNPCC is characterized by early disease onset. Rectal cancer and ascending colon cancer are the first and the secondly common cancer for Chinese HNPCC. Gastric cancer is the most common parenteral cancer in Chinese HNPCC families.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Prognóstico
/
Neoplasias Colorretais Hereditárias sem Polipose
/
China
/
Epidemiologia
/
Incidência
/
Taxa de Sobrevida
/
Povo Asiático
/
Genética
Tipo de estudo:
Estudo de incidência
/
Estudo prognóstico
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
País/Região como assunto:
Ásia
Idioma:
Chinês
Revista:
Chinese Journal of Gastrointestinal Surgery
Ano de publicação:
2005
Tipo de documento:
Artigo
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