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Preparation, in vitro evaluation of excipient-free dry powder inhalation of extraction of Trollius chinensis / 中国中药杂志
China Journal of Chinese Materia Medica ; (24): 2096-2100, 2013.
Artigo em Chinês | WPRIM | ID: wpr-346435
ABSTRACT
To prepare and evaluate dry powder inhalation (DPI) of extraction of Trollius chinensis Bunge (TCB). Orthodox design was employed to optimize the parameters of spray drying to prepare micronized TCB powder, the DPI was prepared by mixing micronized TCB powder and lactose. The results showed that the fine particle fraction (FPF) and emitted dose (ED) of micronized TCB powder was (21.07 +/- 1.74)%, (75.31 +/- 21.05)%, respectively, and for DPI was (56.4 +/- 2.2)%, (95.9 +/- 3.0)%, respectively. Therefore, the prepared DPI meeted requirements in the Chinese Pharmacopeia, indicating a good application prospect.
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Pós / Administração por Inalação / Extratos Vegetais / Ranunculaceae / Excipientes / Inaladores de Pó Seco Idioma: Chinês Revista: China Journal of Chinese Materia Medica Ano de publicação: 2013 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Pós / Administração por Inalação / Extratos Vegetais / Ranunculaceae / Excipientes / Inaladores de Pó Seco Idioma: Chinês Revista: China Journal of Chinese Materia Medica Ano de publicação: 2013 Tipo de documento: Artigo