Effect of hydrostatic pressure on ultrastructure of synovial fibroblasts from rat temporomandibular joint / 中华口腔医学杂志
Chinese Journal of Stomatology
;
(12): 754-755, 2008.
Artigo
em Chinês
| WPRIM
| ID: wpr-346792
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the role of apoptosis in the remodeling of temporomandibular joint (TMJ) under pressure.</p><p><b>METHODS</b>Synovial fibroblasts obtained from rat temporomandibular joint were subjected to different hydrostatic pressure for 12 h. Changes of ultrastructure were observed by transmission electron microscope.</p><p><b>RESULTS</b>At 30 kPa, the ultrastructure of synovial fibroblasts showed no obvious changes. At 60 kPa, the chromatin was condensated, the baryon took on crescent and the mitochondria seemed varicose. At 90 kPa, the apoptosis-like body was wrapped by membrane and embedded in the high density chromatin.</p><p><b>CONCLUSIONS</b>Apoptosis-like change took place in ultrastructure of synovial fibroblasts under hydrostatic pressure, and the degree of the change was related to the hydrostatic pressure exerted.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Membrana Sinovial
/
Articulação Temporomandibular
/
Ratos Sprague-Dawley
/
Apoptose
/
Biologia Celular
/
Fibroblastos
/
Pressão Hidrostática
Limite:
Animais
Idioma:
Chinês
Revista:
Chinese Journal of Stomatology
Ano de publicação:
2008
Tipo de documento:
Artigo
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