Advance in studies on effect of paeoniflorin on nervous system / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 297-301, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-346829
ABSTRACT
Paeoniflorin (PF) is the chief active component of paeonia, with diverse pharmacological actions and wide application. Recently, the effect of PF on nervous system has attracted increasingly more attention. According to current study findings, PF can ameliorate the decline of memory and learning capacities in many dementia model animals, and have effect in protecting the cerebral ischemia injury, treating Parkinson's disease, reliving pain and improving neural synapse plasticity. Thought its mechanism has not been clarified, current findings show that adenosine A1 receptor plays an important role, while M cholinergic receptor, opiate receptor, calcium ion channel and NF-KB may also play a part in paeoniflorin's effect on nervous system.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Benzoatos
/
Hidrocarbonetos Aromáticos com Pontes
/
Canais de Cálcio
/
NF-kappa B
/
Monoterpenos
/
Receptor A1 de Adenosina
/
Glucosídeos
/
Aprendizagem
/
Memória
Tipo de estudo:
Estudo prognóstico
Limite:
Animais
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2013
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS