Preparation of submicron emulsion of fresh Zhongjiefeng volatile oil / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 3199-3202, 2009.
Artigo
em Chinês
| WPRIM
| ID: wpr-346918
ABSTRACT
<p><b>OBJECTIVE</b>To prepare the submicron emulsion of fresh Zhongjiefeng volatile oil.</p><p><b>METHOD</b>The Zhongjiefeng volatile oil submicron emulsion was obtained after passing the elementary emulsion through a high pressure homogenizer. The physical and chemical stability of the emulsion was evaluated with the stability parameter of centrifugation, appearance of emulsion and the pH. The formulation and processing factors were optimized by single factor reviewing and orthogonal experimental design.</p><p><b>RESULT</b>By controlling various processing factors and optimizing formulation, the stable submicron emulsion of Zhongjiefeng volatile oil was prepared. Its mean particle diameter was 164-169 nm with PDI 0.084-0.107 and Zeta electric potential was -40 mV.</p><p><b>CONCLUSION</b>The formulation and preparation technique of the emulsion is reasonable.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Óleos Voláteis
/
Medicamentos de Ervas Chinesas
/
Química
/
Estabilidade de Medicamentos
/
Emulsões
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2009
Tipo de documento:
Artigo
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