Measurment of Functioning Hepatocyte Mass using Cardiac Blood Pool Clearance Rates of 99mTc-DISIDA
Journal of the Korean Radiological Society
; : 583-587, 1994.
Article
em Ko
| WPRIM
| ID: wpr-34710
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: The authors investigated the ability of cardiac blood pool clearance rates(CBCR) of 99mTc-DiSiDA in the measure merit of functioning hepatocyte mass. MATERIALS AND METHODS: We measured the volume of Iobectomized liver after completion of postoperative scanning with CBCR of 99rnTc-DISIDA in 5 rabbits who the functional hepatic Iobectomy performed by ligation of hepatic artery, portal vein and biliary tracts. Regarding the measurement of CBCR of 99mTc-DISIDA, we set the time which was decreased to the half of the clearance amount of the cardiac radioactivity by hepatic extraction of 99mTc-DISIDA at the point of 50 sec after the renal peak of the radioactivity to prevent confusing with the blood dilution of the radioactivity, that have called DI-K50. RESULTS: The results were followed that the volumes of the functional hepatic Iobectomy in 5 rabbits were 25%, 25%, 41%, 52%, 75% and the residual functioning hepatocyte masses measured by CBCR of 99rnTc-DISIDA were preserved to 75. 1%, 70. 8%, 63. 0%, 52. 2%, 30. 8% respectively. CONCLUSION: we made decision that CBCR of 99rnTc-DISlDA was useful to evaluate the functioning hepatocyte mass.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Veia Porta
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Radioatividade
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Sistema Biliar
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Disofenina Tecnécio Tc 99m
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Hepatócitos
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Artéria Hepática
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Ligadura
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Fígado
Limite:
Animals
Idioma:
Ko
Revista:
Journal of the Korean Radiological Society
Ano de publicação:
1994
Tipo de documento:
Article