A clinical and histological study of Bio-Oss in combination with guided bone regeneration membrane technique / 中华口腔医学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To evaluate the reliability of Bio-Oss particles as bone grafts in combination with membrane-technique.</p><p><b>METHODS</b>6 small biopsy specimens were retrieved without causing iatrogenic damage in 6 patients (implant sites). The Donath's hard tissue section and micro grinding technique was adopted, and Leval Laczko staining method was used.</p><p><b>RESULTS</b>The histological results showed Bio-Oss particles were easily distinguished from the newly formed bone, but new bone was formed among different particles of Bio-Oss, no connective tissue was found. Intimate contact between newly formed bone and particles of the graft was present.</p><p><b>CONCLUSIONS</b>Bio-Oss appears to be highly biocompatible and osteoconductive. It can be used success fully as a bone substitute in combination with guided bone regeneration membrane technique.</p>