The relativity between Streptococcus sanguis group and coronary heart disease / 中华口腔医学杂志
Chinese Journal of Stomatology
;
(12): 222-224, 2002.
Artigo
em Inglês
| WPRIM
| ID: wpr-347388
ABSTRACT
<p><b>OBJECTIVE</b>To study the relativity between Streptococcus sanguis group (SSG) and coronary heart disease (CHD).</p><p><b>METHODS</b>41 individuals were diagnosed with CHD and 18 normals served as controls. All of them had undergone coronary angiography. Their social class (including education and wages), smoking, drinking, blood lipids and oral health were also recorded. SSG in saliva and subgingival plaque were cultivated in NAYS-B agar plates and counted. SSG were identified into species with routine biochemical reaction and AP-PCR.</p><p><b>RESULTS</b>In the multiple step regression analysis, the amount of SSG in saliva and subgingival plaque were positively associated with severe coronary atheromatosis after adjusting the classical risk factors of CHD. The average amount of SSG in saliva was (435 +/- 422) x 10(8) CFU/L in CHD group and (358 +/- 540) x 10(8) CFU/L in control group, F = 2.72, P = 0.08; the average amount of SSG in incisor was (331 +/- 484) x 10(7) CFU/L in CHD group and (98 +/- 164) x 10(7) CFU/L in control group, F = 5.54, P = 0.02; the average amount of SSG in molar was (352 +/- 381) x 10(7) CFU/L in CHD group and (185 +/- 232) x 10(7) CFU/L in control group, F = 2.86, P = 0.10. S. sanguis and S. gordonii were more in CHD group than in control group (P < 0.05), whereas S. mitis and S. oralis were the same in two groups (P > 0.05).</p><p><b>CONCLUSION</b>The increase of SSG in oral floras may play an important role in the occurrence of CHD.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Saliva
/
Fatores Socioeconômicos
/
Infecções Estreptocócicas
/
Streptococcus sanguis
/
Fumar
/
Fatores de Risco
/
Estatística como Assunto
/
Doença das Coronárias
/
Placa Dentária
/
Escolaridade
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
/
Fatores de risco
Limite:
Idoso
/
Humanos
Idioma:
Inglês
Revista:
Chinese Journal of Stomatology
Ano de publicação:
2002
Tipo de documento:
Artigo
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