Alternation and significance of CD4(+)CD45RA(+) and CD4(+)CD45RO(+) T cells in peripheral blood of colorectal cancer patients / 中华肿瘤杂志
Chinese Journal of Oncology
;
(12): 362-364, 2003.
Artigo
em Chinês
| WPRIM
| ID: wpr-347424
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the alternation and significance of CD4(+)CD45RA(+) T cells and CD4(+)CD45RO(+) T cells in peripheral blood of colorectal cancer patients.</p><p><b>METHODS</b>The expression of CD4(+) T cells, CD4(+)CD45RA(+) T cells and CD4(+)CD45RO(+) T cells in peripheral blood of 60 colorectal cancer patients were detected with flow cytometry pre-operatively and 1, 3 months post-operatively, compared with those of 10 healthy persons.</p><p><b>RESULTS</b>CD4(+) T cells expression of colorectal cancer patients was the same as the healthy persons. The proportion of CD4(+)CD45RO(+) T cells of colorectal cancer patients was higher, which descended post-operatively, especially in Dukes A and B patients, while CD4(+)CD45RA(+) T cells showed the opposite findings.</p><p><b>CONCLUSION</b>CD4(+)CD45RA(+) T cells and CD4(+)CD45RO(+) T cells, playing an important immune effect in colorectal cancer patients, is closely related to stage and prognosis.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Período Pós-Operatório
/
Prognóstico
/
Cirurgia Geral
/
Sangue
/
Neoplasias Colorretais
/
Linfócitos T CD4-Positivos
/
Antígenos Comuns de Leucócito
/
Alergia e Imunologia
/
Estadiamento de Neoplasias
Tipo de estudo:
Estudo prognóstico
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Oncology
Ano de publicação:
2003
Tipo de documento:
Artigo
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