Neuroimaging of Hemichorea-Hemiballism
Journal of the Korean Neurological Association
;
: 318-323, 2007.
Artigo
em Coreano
| WPRIM
| ID: wpr-34780
ABSTRACT
BACKGROUND:
Hemichorea-Hemiballism (HCHB) can be caused by various diseases such as cerebrovascular disease, hyperglycemia, tumor, and inflammatory diseases. However, there are a few case studies using functional imaging such as single photon emission computed tomography (SPECT).METHODS:
In this study, we included patients with HCHB. The patients with hyperglycemia over 250 mg/dl or high signal intensity on T1 weighted imaging were excluded. Clinical and neuroimaging characteristics of the patients were obtained and analyzed.RESULTS:
We included 20 patients (MF=128, mean age=67.1+/-15.3). Sixteen patients were presented with hemiballism and four with hemichorea. Six patients had no structural lesions causing HCHB. Subthalamic nucleus was the causative lesion in 6 patients. Other lesions associated with HCHB were basal ganglia, thalamus, and cortices. In a patient without structural lesion, anti-double stranded DNA antibody was detected. Brain SPECT showed not only perfusion abnormalities in the cases without structural lesions but also additional abnormalities in those with definite lesions.CONCLUSIONS:
Various mechanisms were related to the development of HCHB. Functional imaging such as SPECT and immunological work-up is needed to investigate the underlying pathomechanism of HCHB.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Perfusão
/
Tálamo
/
Gânglios da Base
/
Encéfalo
/
DNA
/
Tomografia Computadorizada de Emissão de Fóton Único
/
Núcleo Subtalâmico
/
Discinesias
/
Neuroimagem
/
Hiperglicemia
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Neurological Association
Ano de publicação:
2007
Tipo de documento:
Artigo
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