Predicting factors of present hepatitis C virus infection among patients positive for the hepatitis C virus antibody
Clinical and Molecular Hepatology
;
: 376-381, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-34828
ABSTRACT
BACKGROUND/AIMS:
To identify the predicting factors of present hepatitis C virus (HCV) infection among patients with positivity for antibodies to HCV (anti-HCV).METHODS:
We analyzed patients who showed positive enzyme immunoassay (EIA) results and performed an HCV RNA test as a confirmatory test at Kyung Hee University Hospital at Gangdong from June 2006 to July 2012. The features distinguishing the groups with positive and negative HCV RNA results were reviewed.RESULTS:
In total, 490 patients were included. The results of the HCV RNA test were positive and negative in 228 and 262 patients, respectively. The index value of anti-HCV, mean age, platelet counts, total bilirubin, prothrombin time international normalized ratio, albumin and alanine transaminase (ALT) levels differed significantly between the two groups. On multivariable analysis, an index value of anti-HCV >10 [odds ratio (OR)=397.27, P40 IU/L (OR=3.64, P=0.001), and albumin <3.8 g/dL (OR=2.66, P=0.014) were related to present HCV infection.CONCLUSIONS:
Although EIA is not a quantitative test, considering the anti-HCV titer with ALT and albumin levels may be helpful in predicting present of HCV infection.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Contagem de Plaquetas
/
Bilirrubina
/
RNA Viral
/
Albumina Sérica
/
Razão de Chances
/
Valor Preditivo dos Testes
/
Técnicas Imunoenzimáticas
/
Hepatite C
/
Hepacivirus
/
Anticorpos Anti-Hepatite C
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Clinical and Molecular Hepatology
Ano de publicação:
2013
Tipo de documento:
Artigo
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