Effects of moxibustion preconditioning on SOD and MDA in rats with global brain ischemia / 中国针灸
Chinese Acupuncture & Moxibustion
;
(12): 595-597, 2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-348492
ABSTRACT
<p><b>OBJECTIVE</b>To reveal the mechanism of moxibustion preconditioning in preventive brain-protecting action.</p><p><b>METHODS</b>The rat model of global brain ischemia was made with 4-artery ligation method. 78 Wistar rats were randomly divided into 5 groups normal control group, sham-operation group, brain ischemia group, brain ischemia preconditioning group and moxibustion preconditioning group. The brain was taken 24 h, 48 h and 72 h after operation in the all groups, respectively, for determination of SOD activities by xanthine oxidase method and MDA content by thibabituric acid method.</p><p><b>RESULTS</b>The SOD activity significantly increased, especially 24 h after the moxibustion preconditioning, and the MDA content decreased significantly with a very significant difference as compared with the ischemia group(P<0.01).</p><p><b>CONCLUSION</b>Moxibustion preconditioning exerts the protective action on the brain tissue of ischemia and anoxia through increasing the endogenous anti-oxidase activity.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Encéfalo
/
Isquemia Encefálica
/
Ratos Wistar
/
Isquemia
/
Moxibustão
Limite:
Animais
Idioma:
Chinês
Revista:
Chinese Acupuncture & Moxibustion
Ano de publicação:
2006
Tipo de documento:
Artigo
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