A case-control study on the risk factor of perinatals' congenital malformations in seven cities of Guangxi / 中华流行病学杂志
Chinese Journal of Epidemiology
; (12): 512-515, 2003.
Article
em Zh
| WPRIM
| ID: wpr-348822
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the possible risk factors of congenital malformations in cities of Guangxi.</p><p><b>METHODS</b>A case-control study was carried out on 281 cases of congenital malformations and 730 controls. Analysis of simple factor and multiple factors unconditional logistic regression were done.</p><p><b>RESULTS</b>The analysis of simple factor and multiple factors showed that main risk factors of congenital malformations as multiple pregnancies (OR = 2.6), pregnancy complications (OR = 3.2), exposure to chemical substances before or during pregnancy (OR = 3.0), taking sedatives (OR = 10.2), hormone drug (OR = 9.4) or Chinese herbal medicines (OR = 2.5) during the early stage of pregnancy, mothers' blood type as AB (OR = 3.5) or A (OR = 2.2), mothers' emotion being nervous and melancholy (OR = 2.6), mothers' occupation being workers (OR = 3.8) or peasants (OR = 3.0), fathers' exposure to noise (OR = 5.7) or suffering from chronic diseases (OR = 2.8).</p><p><b>CONCLUSIONS</b>Some risk factors were identified as having important effect on perinatal congenital malformations, including taking sedatives, hormone drug or Chinese herbal medicines during the early stage of pregnancy, mothers' emotion being nervous and melancholy, multiple pregnancies, pregnancy complications, exposure to chemical substances before or during pregnancies, mothers' blood type as AB or A, mothers' occupation being workers or peasants, fathers' exposure to noise or suffering from chronic diseases.</p>
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Anormalidades Congênitas
/
Estudos de Casos e Controles
/
Modelos Logísticos
/
Fatores de Risco
Tipo de estudo:
Etiology_studies
/
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Female
/
Humans
/
Male
/
Newborn
Idioma:
Zh
Revista:
Chinese Journal of Epidemiology
Ano de publicação:
2003
Tipo de documento:
Article