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A case-control study on the risk factor of perinatals' congenital malformations in seven cities of Guangxi / 中华流行病学杂志
Chinese Journal of Epidemiology ; (12): 512-515, 2003.
Article em Zh | WPRIM | ID: wpr-348822
Biblioteca responsável: WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the possible risk factors of congenital malformations in cities of Guangxi.</p><p><b>METHODS</b>A case-control study was carried out on 281 cases of congenital malformations and 730 controls. Analysis of simple factor and multiple factors unconditional logistic regression were done.</p><p><b>RESULTS</b>The analysis of simple factor and multiple factors showed that main risk factors of congenital malformations as multiple pregnancies (OR = 2.6), pregnancy complications (OR = 3.2), exposure to chemical substances before or during pregnancy (OR = 3.0), taking sedatives (OR = 10.2), hormone drug (OR = 9.4) or Chinese herbal medicines (OR = 2.5) during the early stage of pregnancy, mothers' blood type as AB (OR = 3.5) or A (OR = 2.2), mothers' emotion being nervous and melancholy (OR = 2.6), mothers' occupation being workers (OR = 3.8) or peasants (OR = 3.0), fathers' exposure to noise (OR = 5.7) or suffering from chronic diseases (OR = 2.8).</p><p><b>CONCLUSIONS</b>Some risk factors were identified as having important effect on perinatal congenital malformations, including taking sedatives, hormone drug or Chinese herbal medicines during the early stage of pregnancy, mothers' emotion being nervous and melancholy, multiple pregnancies, pregnancy complications, exposure to chemical substances before or during pregnancies, mothers' blood type as AB or A, mothers' occupation being workers or peasants, fathers' exposure to noise or suffering from chronic diseases.</p>
Assuntos
Texto completo: 1 Índice: WPRIM Assunto principal: Anormalidades Congênitas / Estudos de Casos e Controles / Modelos Logísticos / Fatores de Risco Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male / Newborn Idioma: Zh Revista: Chinese Journal of Epidemiology Ano de publicação: 2003 Tipo de documento: Article
Texto completo: 1 Índice: WPRIM Assunto principal: Anormalidades Congênitas / Estudos de Casos e Controles / Modelos Logísticos / Fatores de Risco Tipo de estudo: Etiology_studies / Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Female / Humans / Male / Newborn Idioma: Zh Revista: Chinese Journal of Epidemiology Ano de publicação: 2003 Tipo de documento: Article