Carcinoma with Predominant Lymphoid Stroma in Hepatobiliary System: Report of 2 Cases / 대한간학회지
The Korean Journal of Hepatology
;
: 222-227, 2007.
Artigo
em Coreano
| WPRIM
| ID: wpr-34943
ABSTRACT
Lymphoepithelioma-like carcinoma (LELC) is an undifferentiated carcinoma with predominant lymphocytic infiltration, which is associated with Epstein-Barr virus (EBV) in variable proportions. We report two cases of carcinoma with predominant lymphoid stroma in hepatobiliary system. The first case was a lymphoepithelioma-like undifferentiated carcinoma with focal differentiation of cholangiocarcinoma (cytokeratin 19+) and hepatocellular carcinoma in light microscopy. The infiltration of CD8+ T lymphocytes was observed in the tumor and the surrounding hepatic parenchyme. In this tumor, EBV was detected and LMP1 was positive immunohistochemically. The second case showed the mixed features of lymphoepithelioma-like carcinoma and cholangiocarcinoma with predominant lymphoid stroma. In this case, EBV was detected. LELC of hepatobiliary system is an entity distinguished from conventional carcinoma with lymphoid stroma, and its association with EBV warrants further research.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Neoplasias dos Ductos Biliares
/
Ductos Biliares Intra-Hepáticos
/
Carcinoma
/
Tomografia Computadorizada por Raios X
/
Linfócitos do Interstício Tumoral
/
Colangiocarcinoma
/
Herpesvirus Humano 4
/
Linfócitos T CD8-Positivos
/
Neoplasias Hepáticas
Limite:
Humanos
/
Masculino
Idioma:
Coreano
Revista:
The Korean Journal of Hepatology
Ano de publicação:
2007
Tipo de documento:
Artigo
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