Discovery of MHC restriction in antigen recognition of T cells / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 539-541, 2002.
Article
em Zh
| WPRIM
| ID: wpr-350066
Biblioteca responsável:
WPRO
ABSTRACT
T cell can only recognize specific antigenic peptide-MHC complex on antigen-presenting cell. This is MHC restriction in antigen recognition of T cell. This phenomenon was discovered by an Austrian scientist Peter. C. Doherty and a Swedish scientist Rolf. M. Zinkernagel by chance. Then, in order to explain the phenomenon, they proposed two hypotheses: dual receptor and modified self. In the during following 20 years numbers of scientists spent great amount of time in the study of the phenomenon. The process of cell-mediated immune response becomes clear, which greatly promotes the advancing of immunology and many related disciplines.
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Receptores de Antígenos de Linfócitos T
/
Linfócitos T
/
Alergia e Imunologia
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Imunidade Celular
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Complexo Principal de Histocompatibilidade
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Células Apresentadoras de Antígenos
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Epitopos
Limite:
Animals
/
Humans
Idioma:
Zh
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2002
Tipo de documento:
Article