Effects of Yifuning capsule on blood lipids of ovariectomized hyperlipidemia rats / 中国中药杂志
China Journal of Chinese Materia Medica
; (24): 414-416, 2006.
Article
em Zh
| WPRIM
| ID: wpr-350925
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ABSTRACT
<p><b>OBJECTIVE</b>To observe the effects of Yifuning (YEN) capsule on blood lipids of ovariectomized hyperlipidemia rats.</p><p><b>METHOD</b>Fifty-six female mature Sprague-Dawley rats were randomized into 7 groups: normal control group, model control group, diethylstilbestrol tablets (DT) group, Xuezhikang group, YFN high, middle and low dose groups. The ovariectomized rats were fed on high fat diet and administrated with the drugs for 3 weeks, then were killed and estimated body weight, liver index and five items of blood lipid (TC, TG, HDL-C, LDL-C, VLDL) by test kit. Enzyme (such as HP, LDL, and whole lipase) was detected too.</p><p><b>RESULT</b>The weight and liver index of model control group increased obviously as compared with normal group. YFN could reduce TG, TC, and LDL-C (P < 0.05) of ovariectomized hyperlipidemia rats obviously and increase HP, LDL and whole lipase (P < 0.05) on the other hand.</p><p><b>CONCLUSION</b>YFN can ameliorate blood lipids of ovariectomized hyperlipidemia rats.</p>
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Assunto principal:
Oviductos
/
Farmacologia
/
Ranidae
/
Sangue
/
Cápsulas
/
Medicamentos de Ervas Chinesas
/
Materia Medica
/
Ovariectomia
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Distribuição Aleatória
/
Química
Tipo de estudo:
Prognostic_studies
Limite:
Animals
Idioma:
Zh
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2006
Tipo de documento:
Article