Screening of glucosidase inhibitors from various fractions of Mulberry leaves / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 223-227, 2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-350968
ABSTRACT
<p><b>OBJECTIVE</b>To search for glucosidase inhibitors of various fractions extracted from mulberry leaves.</p><p><b>METHOD</b>The constituents of mulberry leaves water fraction were prepared by the process of boiling, condensing, precipitating, exchanging with resins and rinsing. In vitro glucosidase inhibitory activities were examined by photometric bioassay derived from rats. To investigate in vivo effect of lowering blood glucose, the mouse blood glucose level was assayed by glucose tolerance experiments.</p><p><b>RESULT</b>The glucosidase inhibitory activities were found in all the constituents of alkaloids, flavones and amyloses, the alkaloid constituent being the strongest.</p><p><b>CONCLUSION</b>The effect of reducing blood glucose of mulberry leaves is related to the inhibitory activities against glucosidase of different constituents.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Plantas Medicinais
/
Química
/
Folhas de Planta
/
Morus
/
Flavonas
/
Diabetes Mellitus Experimental
/
Alcaloides
/
Alfa-Glucosidases
/
Inibidores de Glicosídeo Hidrolases
Tipo de estudo:
Estudo diagnóstico
/
Estudo de rastreamento
Limite:
Animais
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2006
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS