Studies on chemical constituents of Patrinia villosa / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the chemical constituents of Patrinia villosa.</p><p><b>METHOD</b>The chemical constituents were isolated by silica gel column chromatography and semi-preparative high-performance liquid chromatography, and identified by physicochemical properties and spectral analysis (MS, 1H-NMR and 13C-NMR).</p><p><b>RESULT</b>Seven compounds were isolated from ethyl acetate and n-butanol extract and identified as 5-hydroxyl-7, 3', 4'-trimethoxy flavone (I), 5-hydroxyl-7, 4'-dimethoxy flavone (II), luteolin (III), quercetin (IV), isoorientin (V), isovitexin (VI) and 8-C glucosylprunetin (VII).</p><p><b>CONCLUSION</b>Compounds I , II, III, V, VI and VIII were obtained from the plant of genus Patrinia for the first time, compound IV was separated from P. villosa for the first time.</p>