A preliminary study of renal function in small-for-gestational-age infants at early stage after birth / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
; (12): 389-392, 2017.
Article
em Zh
| WPRIM
| ID: wpr-351338
Biblioteca responsável:
WPRO
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the renal function of small-for-gestational-age (SGA) infants at the early stage after birth.</p><p><b>METHODS</b>A total of 40 preterm SGA infants, 33 full-term SGA infants, 80 preterm appropriate-for-gestational-age (AGA) infants, and 33 full-term AGA infants were included in this study. The following indices were compared between the SGA infants and AGA infants within 48 hours after admission: blood urea nitrogen (BUN), serum creatinine (SCr), estimated glomerular filtration rate (eGFR), blood pressure, urine volume per body weight, and proteinuria.</p><p><b>RESULTS</b>The preterm SGA group had a significantly lower BUN level than the preterm AGA group (P<0.05). However, there were no significant differences in SCr level, eGFR, and blood pressure between the two groups (P>0.05). The full-term SGA group had a significantly higher SCr level and a significantly lower eGFR than the full-term AGA group (P<0.05). However, there were no significant differences in BUN level and blood pressure between the two groups (P>0.05). There was no significant difference in urine volume per body weight between the preterm SGA and preterm AGA groups (P>0.05) and between the full-term SGA and full-term AGA groups (P>0.05). There was no significant difference in the incidence of proteinuria between the preterm SGA and preterm AGA groups (P>0.05). Proteinuria was not present in the SGA full-term and AGA full-term groups.</p><p><b>CONCLUSIONS</b>SCr and eGFR can be used as the diagnostic indices for early renal damage of SGA infants. The renal function is worse in full-term SGA infants than in full-term AGA infants.</p>
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Índice:
WPRIM
Assunto principal:
Fisiologia
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Sangue
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Recém-Nascido Pequeno para a Idade Gestacional
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Estudos Retrospectivos
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Creatinina
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Retardo do Crescimento Fetal
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Taxa de Filtração Glomerular
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Rim
Tipo de estudo:
Observational_studies
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Risk_factors_studies
Limite:
Female
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Humans
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Infant
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Male
Idioma:
Zh
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2017
Tipo de documento:
Article