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Bioactive isomalabaricane triterpenes isolated from marine sponge Rhabdastrella aff. distincta / 中国中药杂志
China Journal of Chinese Materia Medica ; (24): 894-898, 2006.
Artigo em Chinês | WPRIM | ID: wpr-351822
ABSTRACT
<p><b>OBJECTIVE</b>To study the chemical constituents of the marine sponge Rhabdastrella aff. distincta.</p><p><b>METHOD</b>Compounds were obtained by normal phase silica gel, Sephadex LH-20, reverse phase chromatogrophy and methylation method. These structures were determined on the basis of IR, MS, NMR spectral analysis.</p><p><b>RESULT</b>Eight compounds were isolated from bioactive CH3Cl fraction and identified as geoditin A (1), geoditin B (2), stellettin A (5), stellettin B (4), stellettin C (3), stellettinE (7), rhabdastrellic acid A (8) and the methyl ester of stellettin E (6).</p><p><b>CONCLUSION</b>All these compounds were obtained from this species for the first time.</p>
Assuntos
Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Farmacologia / Poríferos / Resorcinóis / Triterpenos / Materia Medica / Células Tumorais Cultivadas / Células HeLa / Química / Células HL-60 / Antineoplásicos Limite: Animais / Humanos Idioma: Chinês Revista: China Journal of Chinese Materia Medica Ano de publicação: 2006 Tipo de documento: Artigo

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Texto completo: DisponíveL Índice: WPRIM (Pacífico Ocidental) Assunto principal: Farmacologia / Poríferos / Resorcinóis / Triterpenos / Materia Medica / Células Tumorais Cultivadas / Células HeLa / Química / Células HL-60 / Antineoplásicos Limite: Animais / Humanos Idioma: Chinês Revista: China Journal of Chinese Materia Medica Ano de publicação: 2006 Tipo de documento: Artigo