A brief report on effect of rhG-CSF in treating leukopenia after radio-and chemo-therapy of patients with breast cancer / 中国实验血液学杂志
Journal of Experimental Hematology
;
(6): 381-382, 2004.
Artigo
em Chinês
| WPRIM
| ID: wpr-352059
ABSTRACT
The study was to observe the effect of rhG-CSF (lishengsu) in treating leukopenia caused by radiotherapy and chemotherapy in patients with breast cancer. 100 cases of breast cancer received modified radical mastectomy were randomized into two groups with the same treatment of one cycle chemotherapy using the protocol of CAF at two weeks after the operations and then radiotherapy. The patients in treated group received rhG-CSF 75 micro g per day s.c. for 5 - 7 days constantly, and additional 3 - 5 days according to leukopenia during radiotherapy. The patients in control group did not receive rhG-CSF during the chemo- and radio-therapy. The results shows that nadir of WBC and neutrophil counts in the treated group was higher than that in control significantly. In conclusion, effect of lishengsu on leucopenia in process of chemotherapy and radiotherapy shows definite therapeutic effect, the side effects are not remarkable.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Terapêutica
/
Proteínas Recombinantes
/
Neoplasias da Mama
/
Fator Estimulador de Colônias de Granulócitos
/
Terapia Combinada
/
Usos Terapêuticos
/
Tratamento Farmacológico
/
Leucopenia
Tipo de estudo:
Ensaio Clínico Controlado
/
Guia de Prática Clínica
Limite:
Adulto
/
Feminino
/
Humanos
Idioma:
Chinês
Revista:
Journal of Experimental Hematology
Ano de publicação:
2004
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS