Comparative analysis of dual resource computed tomography angiography and 3.0T magnetic resonance angiography in the diagnosis of intracranial aneurysms / 生物医学工程学杂志

ABSTRACT

To comparatively study the diagnostic value of dual resource computed tomography angiography (DSCTA) and 3.0T magnetic resonance angiography (MRA) for intracranial aneurysm, we analyzed retrospectively radiographic data of DSCTA, 3.0T MRI and three dimensional digital subtraction angiography (3D DSA ) in cases suspected intracranial aneurysms during Jan. 2010 to Dec. 2011. With 3D DSA as "gold standard", the sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of DSCTA and 3.0T MRA in diagnostic of intracranial aneurysms were analyzed, and the accuracy of both methods on evaluation of aneurysms size was compared as well. Totally fifty-three suspected cases were included, and forty-two intracranial aneurysms in thirty-five cases were identified by 3D DSA. For DSCTA, 37 aneurysms were detected in 32 patients, and 3 patients and 5 aneurysms were missed in all patients. However, for 3.0 T MRA, 33 aneurysms were detected in 33 patients, 5 patients and 8 aneurysms were missed, and 3 patients who did not have aneurysms were misdiagnosed as ones with intracranial aneurysms. The sensitivity, specificity, positive predictive value, negative predictive value, and accuracy of DSCTA and 3.0T MRA were 91.4% vs. 85.7%, 100% vs. 83.3%, 100% vs. 90.9%, 85.7% vs. 75.0% and 94.3% vs. 84.9%,respectively. There was no significant difference in evaluation of aneurysms size between using the two methods. Data suggested that both DSCTA and 3.0T MRA had high accuracy for detection intracranial aneurysms and evaluation of aneurysms size, but as for detection of microaneurysms, DSCTA was superior to 3.0T MRA.