Change of Epithelial Barrier Function after Excimer Laser Photorefractive Keratectomy
Journal of the Korean Ophthalmological Society
; : 1119-1124, 1998.
Article
em Ko
| WPRIM
| ID: wpr-35244
Biblioteca responsável:
WPRO
ABSTRACT
We used the fluorophotometry to investigate the corneal epithelial barrier function after excimer laser photorefractive keratectomy (PRK). Twenty-five eyes of 21 subjects (13 women, 8 men) underwent PRK to correct rnyopia. Corneal epithelial healing time was measured and corneal epithelial permeability to sodiurn fluorescein was evaluated by fluorophotoinetry at I, 2, and 3 weeks after surgery. The corneal epithelial permeability increased significantly 1 week after surgery and returned to preoperative level 2 weeks after surgery. The permeability differences according to epithelial healing days and corrected diopters were not statistically significant(p>0. 05). These results suggest that PRK delays complete reconstruction of corneal epithelial barrier function. The corneal epithelium regained its functional barrier 2 weeks after PRK in patients, so, at least, during the first 2 weeks, care should be taken to miniinize further epithelial trauma from topical inedication or surgical manipulation.
Palavras-chave
Texto completo:
1
Índice:
WPRIM
Assunto principal:
Permeabilidade
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Fluorofotometria
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Ceratectomia Fotorrefrativa
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Epitélio Corneano
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Fluoresceína
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Lasers de Excimer
Limite:
Female
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Humans
Idioma:
Ko
Revista:
Journal of the Korean Ophthalmological Society
Ano de publicação:
1998
Tipo de documento:
Article