Polycomb group proteins and their roles in regulating stem cell development / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
;
(6): 281-285, 2012.
Artigo
em Inglês
| WPRIM
| ID: wpr-352914
ABSTRACT
Polycomb group (PcG) proteins are a family of epigenetic regulators responsible for the repression of genes in proliferation and differentiation of stem cells. PcG protein complex consists of two important epigenetic regulators PRC1 (polycomb repressive complex 1) and PRC2 (polycomb repressive complex 2). In order to further understand the functions of PcG proteins in stem cell growth and differentiation, we review the PcG protein composition, PcG protein localization in the target gene, PcG protein recruitment, and the functions of PcG proteins in the development of stem cells.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Células-Tronco
/
Diferenciação Celular
/
Biologia Celular
/
Proliferação de Células
/
Proteínas do Grupo Polycomb
/
Complexo Repressor Polycomb 1
/
Complexo Repressor Polycomb 2
/
Metabolismo
Limite:
Humanos
Idioma:
Inglês
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2012
Tipo de documento:
Artigo
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