The chemical constituents of Ligularia pleurocaulis / 药学学报
Acta Pharmaceutica Sinica
;
(12): 529-532, 2005.
Artigo
em Inglês
| WPRIM
| ID: wpr-353480
ABSTRACT
<p><b>AIM</b>To study the chemical constituents of the underground part of Ligularia pleurocaulis (Franch.) Hand-Mazz.</p><p><b>METHODS</b>The dried roots and rhizomes of L. pleurocaulis were extracted with methanol. Isolation and purification were performed by silica gel column chromatography and recrystallization etc. Structures of the pure compounds were established on basis of spectral analysis.</p><p><b>RESULTS</b>Twelve compounds were obtained from L. pleurocaulis, they were 6-angeloyloxy-furanoligularenone (1), 2-oxo-3-hydroxy-eremophila-1(10),3,7(11),8-tetraen-8,12-olide (2), tiglic acid (3), oleanolic acid (4), lupeol (5), beta-sitosterol (6), daucosterol (7), caffeic acid (8), emodin (9), 7-methoxy-coumarin (10), ferulic acid (11) and 4-hydroxy-2,5-dimethoxy-benzaldehyde (12).</p><p><b>CONCLUSION</b>Compound 1 is a new eremophilane and compound 2 is a new natural compound. All above compounds were obtained for the first time from L. pleurocaulis.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Ácido Oleanólico
/
Plantas Medicinais
/
Sesquiterpenos
/
Crotonatos
/
Estrutura Molecular
/
Química
/
Raízes de Plantas
/
Asteraceae
/
Rizoma
/
Conformação Molecular
Idioma:
Inglês
Revista:
Acta Pharmaceutica Sinica
Ano de publicação:
2005
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS