Childhood benign acanthosis nigricans and metabolic abnormality / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 604-606, 2012.
Artigo
em Chinês
| WPRIM
| ID: wpr-353908
ABSTRACT
<p><b>OBJECTIVE</b>To observe the relationship of childhood benign acanthosis nigricans to anthropometric and metabolic indexes, with the aim of studying the association between childhood benign acanthosis nigricans and metabolic diseases.</p><p><b>METHODS</b>A retrospective analysis was performed on the clinical data of 29 children who presented with benign acanthosis nigricans between February 2007 and October 2011. Thirty-two age, sex- and ethnic-matched normal children were selected as control group. The two groups were compared according to obesity (body mass index, waist-to-hip ratio, body fat content and body fat percentage) and metabolic indexes (blood glucose, insulin level and blood lipids).</p><p><b>RESULTS</b>Body mass index, body fat content, body fat percentage, waist-to-hip ratio, fasting blood glucose, insulin level and triglyceride in the 29 patients with benign acanthosis nigricans were higher than in the control group (P<0.05), but the level of high-density lipoprotein in the 29 patients was lower than in the control group (P<0.05). Of the 29 patients, 16 had impaired glucose tolerance and 3 were diagnosed with diabetes (1 case with type 1, two cases with type 2).</p><p><b>CONCLUSIONS</b>Childhood benign acanthosis nigricans is closely associated with obesity, insulin resistance and dyslipidemia.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Resistência à Insulina
/
Estudos Retrospectivos
/
Dislipidemias
/
Acantose Nigricans
/
Doenças Metabólicas
/
Obesidade
Tipo de estudo:
Estudo observacional
Limite:
Adolescente
/
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2012
Tipo de documento:
Artigo
Similares
MEDLINE
...
LILACS
LIS