Protective effect of hydroxysafflor yellow A on endothelial cell injury induced by lipopolysaccharide / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1650-1653, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-354183
ABSTRACT
To observe the protective effect of hydroxyl safflor yellow A (HSYA) on endothelial cell (EC). It has been observed by RT-PCR that HSYA can inhibit the elevation of TNF-alpha, IL-6, ICAM-1 and VCAM-1 mRNA level induced by LPS. The result of immunofluorescence test suggested that HSYA can alleviate p65 subgroup of NF-kappaB nuclear translocation. The experiment on EA-HY926 cell line proved that HSYA can protect EC against inflammation injury.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Quinonas
/
Linhagem Celular
/
Chalcona
/
Lipopolissacarídeos
/
NF-kappa B
/
Interleucina-6
/
Fator de Necrose Tumoral alfa
/
Molécula 1 de Adesão Intercelular
/
Molécula 1 de Adesão de Célula Vascular
Limite:
Humanos
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2011
Tipo de documento:
Artigo
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