Zinc ion implantation-deposition modification of titanium for enhanced adhesion of focal plaques of osteoblast-like cells / 中华医学杂志(英文版)
Chinese Medical Journal
;
(24): 3557-3560, 2013.
Artigo
em Inglês
| WPRIM
| ID: wpr-354435
ABSTRACT
<p><b>BACKGROUND</b>Surface modification by ion implantation-deposition is well established in materials science and can be an effective way to improve biocompatibility. The aim of this study is to evaluate the chemical composition of a modified titanium (Ti) surface after zinc (Zn) ion implantation and deposition and examine the effect of the modification on the formation of cellular focal adhesion plaques in vitro.</p><p><b>METHODS</b>cp-Ti discs were modified with Zn ion implantation and deposition via PIIID. The chemical composition of the surface modification was characterized by X-ray photoelectron spectroscopy (XPS). The formation of focal adhesion plaques on the modified Ti was investigated with human osteoblast-like MG-63 cells that were seeded onto the Ti surfaces and quantified by morphometric analysis under a confocal microscope.</p><p><b>RESULTS</b>XPS data revealed that the modified Zn-Ti surface consisted of Ti, oxygen, Zn, and carbon. In addition, Gaussian fitting of the spectra indicated that the modified surface contained titanium dioxide and zinc oxide. After 6 hours of MG-63 cell culture, there were significantly more focal adhesion plaques on the modified surfaces than observed on the nonmodified Ti (P < 0.05).</p><p><b>CONCLUSION</b>Zn ion implantation and deposition greatly improved the biocompatibility of Ti for the growth of MG-63 cells.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Osteoblastos
/
Farmacologia
/
Titânio
/
Óxido de Zinco
/
Adesão Celular
/
Linhagem Celular
/
Biologia Celular
/
Espectroscopia Fotoeletrônica
Limite:
Humanos
Idioma:
Inglês
Revista:
Chinese Medical Journal
Ano de publicação:
2013
Tipo de documento:
Artigo
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