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Research progress in mechanisms of cellular entry of Japanese encephalitis virus / 病毒学报
Chinese Journal of Virology ; (6): 188-192, 2014.
Article em Zh | WPRIM | ID: wpr-356617
Biblioteca responsável: WPRO
ABSTRACT
Japanese encephalitis virus (JEV) is a pathogenic mosquito-borne flavivirus which is responsible for outbreaks of severe viral encephalitis. The cellular entry of JEV is a prerequisite for Japanese encephalitis, so the understanding of its underlying mechanisms will provide more approaches for treating such disease. In recent years, increasing research has been conducted to investigate the mechanisms of cellular entry of JEV, and the results of research on other flavivirus have expanded the research directions for JEV. More methods will be used to suppress JEV infection because of the development of E protein antibodies and the discovery of several inhibitors of the cellular entry process. This review will summarize the recent advances in the mechanisms of JEV cellular entry and membrane fusion.
Assuntos
Texto completo: 1 Índice: WPRIM Assunto principal: Fisiologia / Virologia / Encefalite Japonesa / Pesquisa Biomédica / Vírus da Encefalite Japonesa (Espécie) / Internalização do Vírus / Genética Limite: Animals / Humans Idioma: Zh Revista: Chinese Journal of Virology Ano de publicação: 2014 Tipo de documento: Article
Texto completo: 1 Índice: WPRIM Assunto principal: Fisiologia / Virologia / Encefalite Japonesa / Pesquisa Biomédica / Vírus da Encefalite Japonesa (Espécie) / Internalização do Vírus / Genética Limite: Animals / Humans Idioma: Zh Revista: Chinese Journal of Virology Ano de publicação: 2014 Tipo de documento: Article