Research advances on thogoto virus of the family orthomyxoviridae / 病毒学报
Chinese Journal of Virology
;
(6): 555-558, 2013.
Artigo
em Chinês
| WPRIM
| ID: wpr-356667
ABSTRACT
Thogoto virus belongs to the family Orthomyxoviridae. It is a tick-borne arbovirus that can infect both human and animals. Thogoto virus's genetic constitution, replication and transcription, and the function of the translated proteins are similar to influenza virus. The studies on Thogoto virus are important for us to better understand the conservative sites of influenza virus. Moreover, the animal model of Thogo-to virus is expected to be an alternative model for highly pathogenic influenza viruses. In the past years, Thogoto virus attracted limited public attention and few studies were engaged in this area. The classification of Thogoto virus, the genetic constitution and evolution, and viral proteins were included in this review. The functions of M protein and ML protein were emphasized, which were translated from the sixth segment and played an important role in viral replication, the interaction between Thogoto virus and host were also highlighted.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Fisiologia
/
Proteínas Virais
/
Virologia
/
Replicação Viral
/
Classificação
/
Thogotovirus
/
Infecções por Orthomyxoviridae
/
Pesquisa Biomédica
/
Interações Hospedeiro-Patógeno
/
Genética
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Virology
Ano de publicação:
2013
Tipo de documento:
Artigo
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