Effect of glaucocalyxin A on level of Th1/Th2 type cytokines in mice / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1257-1260, 2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-356730
ABSTRACT
<p><b>OBJECTIVE</b>To research the effect of glaucocalyxin A (GLA) on the level of Th1/Th2 type cytokines in mice.</p><p><b>METHOD</b>By using flow cytometer with CBA software to detect Th1/Th2 type cytokines.</p><p><b>RESULT</b>GLA had insighificant inhibitory effects on Th1 and Th2 cytokines (IL-2, IFN-gamma,TNF-alpha, IL-4 and IL-5) induced by ConA, in which more potential on cytokines from Th1 than those of from Th2 were displayed. However, GLA could produce inhibition on IL-2, IFN-gamma and TNF-alpha and acceleration on IL-4 and IL-5.</p><p><b>CONCLUSION</b>Immunosuppressive effect of GLA is related to the influence the level of Th1/Th2 type cytokines.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Plantas Medicinais
/
Medicamentos de Ervas Chinesas
/
Química
/
Citocinas
/
Interleucina-4
/
Interleucina-5
/
Interferon gama
/
Interleucina-2
/
Fator de Necrose Tumoral alfa
Limite:
Animais
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2006
Tipo de documento:
Artigo
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