Review about mechanisms of anti-cancer of Solanum nigrum / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 1225-1260, 2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-356741
ABSTRACT
This paper gave a brief introduction of the effect of Solanum nigrum on anti-cancer. The experimental results showed that the total alkaloid isolated from S. nigrum interfered structure and function of tumor cell membrane, disturbed the synthesis of DNA and RNA, changed the cell cycle distribution, so that total alkaloids could play in inhibabition to tumor cells, while the glycoprotein (150 x 10(3)) isolated from S. nigrum might have shown anti-cancer abilities by blocking the anti-apoptotic pathway of NF-kappaB, activating caspase cascades reaction and increasing the production of nitric oxide.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Farmacologia
/
Plantas Medicinais
/
Ácidos Siálicos
/
DNA de Neoplasias
/
RNA Neoplásico
/
Medicamentos de Ervas Chinesas
/
Glicoproteínas
/
Permeabilidade da Membrana Celular
/
Química
/
Solanum nigrum
Limite:
Animais
/
Humanos
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2006
Tipo de documento:
Artigo
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