Inhibitory effect of Panax notoginseng on the VSMC proliferation induced by hyperlipidemia serum / 中国中药杂志

ABSTRACT

<p><b>OBJECTIVE</b>To investigate the effect of P. notoginseng on vascular smooth muscle cell (VSMC) proliferation induced by hyperlipidemia serum.</p><p><b>METHOD</b>MTT method was used to investigate the effect of hyperlipidemia serum and hyperlipidemia plus P. notoginseng on VSMC proliferation.</p><p><b>RESULT</b>Hyperlipidemia serum could promote VSMC proliferation significantly as compared with the control group (P < 0.05), while hyperlipidemia plus P. notoginseng could weaken this effect significantly (P < 0.05).</p><p><b>CONCLUSION</b>P. notoginseng can significantly inhibit the VSMC proliferation induced by hyperlipidemia serum.</p>