Effect of Herba Epimedii flavone on the osteoblasts metabolism in vitro / 中国中药杂志
China Journal of Chinese Materia Medica
;
(24): 487-490, 2006.
Artigo
em Chinês
| WPRIM
| ID: wpr-356785
ABSTRACT
<p><b>OBJECTIVE</b>To explore the effect of Herba Epimedii flavone (HEF) on the osteoblast metabolism in vitro.</p><p><b>METHOD</b>Osteoblast were obtained from new born rat calvaria by digestive enzymes. MTF, PNPP and RT-PCR were used to observe the proliferation, activity of ALP and mRNA expression of OPG and RANKL of cultured osteoblasts in vitro.</p><p><b>RESULT</b>It was found that HEF had the effect on stimulating cell proliferation, activity of ALP and the mRNA expression of OPG of cultured osteoblasts (P < 0.01, P < 0.05).</p><p><b>CONCLUSION</b>HEF can promote the proliferation, the differentiation and the expression of OPG mRNA of the osteoblasts cultured in vitro.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Osteoblastos
/
Farmacologia
/
Plantas Medicinais
/
RNA Mensageiro
/
Glicoproteínas de Membrana
/
Glicoproteínas
/
Proteínas de Transporte
/
Células Cultivadas
/
Química
/
Ratos Sprague-Dawley
Limite:
Animais
Idioma:
Chinês
Revista:
China Journal of Chinese Materia Medica
Ano de publicação:
2006
Tipo de documento:
Artigo
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