A study of aspermia-related genes by genchips and analysis of the RAP1A gene / 中华男科学杂志
National Journal of Andrology
;
(12): 654-657, 2003.
Artigo
em Chinês
| WPRIM
| ID: wpr-357117
ABSTRACT
<p><b>OBJECTIVE</b>To study the differential gene expression profiles between the normal and aspermia human testes by genechips.</p><p><b>METHODS</b>Probes were prepared from mRNA extracted from both normal and aspermia testes and employed on Biostar H-40s genechips to detect the differential gene expression profiles. A distinctly up-regulated gene RAP1A was analyzed by bibliogrphic retrieval.</p><p><b>RESULTS</b>Six hundred and twenty-three differential expressed genes were found, among which the distinctly up-regulated gene RAP1A was closely related to human sperm regulation.</p><p><b>CONCLUSIONS</b>Screening the differential gene expression profiles between the normal and aspermia human testes by genechips can be used in the study of aspermia-related genes.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Oligospermia
/
Análise de Sequência com Séries de Oligonucleotídeos
/
Proteínas rap1 de Ligação ao GTP
/
Perfilação da Expressão Gênica
/
Genética
/
Métodos
Limite:
Adulto
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
National Journal of Andrology
Ano de publicação:
2003
Tipo de documento:
Artigo
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