One Case of Multiple Myeloma with Central Never System Infiltration / 中国实验血液学杂志

ABSTRACT

<p><b>OBJECTIVE</b>To analyses and summarize a case of multiple myeloma with disseminated infiltration in central nervous system.</p><p><b>METHODS</b>The results of laboratorial examination and clinical data were analyzed and compared in the light of published literatures.</p><p><b>RESULTS</b>The headache and diplopia were caused by infiltration of multiple myeloma cells to the central nervous system. Unlike those reported in the literatures, this case was a rare case of disseminated infiltration inside the brain, and plasma cells were CD56+, this patient has not yet accepted any multiple myeloma-associated treatment as like that reported in the literatures. And different from cases reported, this patient showed a good response to the intrathecal chemotherapy.</p><p><b>CONCLUSION</b>Whether this good response is due to a heterogeneity of MM or effect of treatment-associated drug is still to be decided.</p>