Risk factors for bronchopulmonary dysplasia in neonates with respiratory distress syndrome / 中国当代儿科杂志
Chinese Journal of Contemporary Pediatrics
;
(12): 15-18, 2007.
Artigo
em Chinês
| WPRIM
| ID: wpr-357760
ABSTRACT
<p><b>OBJECTIVE</b>To identify the risk factors for bronchopulmonary dysplasia (BPD) in neonates with respiratory distress syndrome (RDS).</p><p><b>METHODS</b>Data from 72 patients with RDS (birth weight 1607 +/- 277 g; gestational age 29.47 +/- 2.54 weeks) who were hospitalized for >28 days and who received mechanical ventilation treatment between January 2001 and August 2005 were studied retrospectively. A logistic regression analysis was used to identify the risk factors associated with the development of BPD.</p><p><b>RESULTS</b>Of the 72 patients, 17 developed BPD (23.6%). Uniovariate analysis revealed that in addition to a gestational age of < or = 30 weeks and a birth weight below 1250 g, the times of mechanical ventilation treatment (> or = 2 times), concurrent pulmonary infection and pneumorrhagia, prolonged mechanical ventilation (> or = 5 days), and positive sputum bacterial cultures on 2 occasions were all associated with an increase in the incidence of BPD. Multivariate logistic analysis revealed that birth weight below 1250 g, prolonged mechanical ventilation (> or = 10 days),and positive sputum cultures on 3 or more occasions were independent risk factors for BPD (OR=6.614,14.997 and 39.752 respectively).</p><p><b>CONCLUSIONS</b>The risk for BPD is multifactorial. Preventing small gestational age and low birth weight prematurity, decreasing the duration of mechanical ventilation and treatment of pulmonary infection are necessary to prevent BPD.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Respiração Artificial
/
Síndrome do Desconforto Respiratório do Recém-Nascido
/
Peso ao Nascer
/
Displasia Broncopulmonar
/
Epidemiologia
/
Incidência
/
Análise Multivariada
/
Estudos Retrospectivos
/
Fatores de Risco
/
Idade Gestacional
Tipo de estudo:
Estudo de etiologia
/
Estudo de incidência
/
Estudo observacional
/
Estudo prognóstico
/
Fatores de risco
Limite:
Feminino
/
Humanos
/
Masculino
/
Recém-Nascido
Idioma:
Chinês
Revista:
Chinese Journal of Contemporary Pediatrics
Ano de publicação:
2007
Tipo de documento:
Artigo
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