Stability Analysis of Susceptible-Infected-Recovered Epidemic Model / 生物医学工程学杂志
Journal of Biomedical Engineering
;
(6): 1013-1018, 2015.
Artigo
em Chinês
| WPRIM
| ID: wpr-357927
ABSTRACT
With the range of application of computational biology and systems biology gradually expanding, the complexity of the bioprocess models is also increased. To address this difficult problem, it is required to introduce positive alternative analysis method to cope with it. Taking the dynamic model of the epidemic control process as research object, we established an evaluation model in our laboratory. Firstly, the model was solved with nonlinear programming method. The results were shown to be good. Based on biochemical systems theory, the ODE dynamic model was transformed into S-system. The eigen values of the model showed that the system was stable and contained oscillation phenomenon. Next the sensitivities of rate constant and logarithmic gains of the three key parameters were analyzed, as well as the robust of the system. The result indicated that the biochemical systems theory could be applied in different fields more widely.
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Teoria de Sistemas
/
Dinâmica não Linear
/
Biologia Computacional
/
Biologia de Sistemas
/
Epidemias
/
Modelos Biológicos
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Biomedical Engineering
Ano de publicação:
2015
Tipo de documento:
Artigo
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