Multiple intracranial lesions: a clinicalpathologic study of 62 cases / 中华病理学杂志
Chinese Journal of Pathology
;
(12): 599-603, 2011.
Artigo
em Chinês
| WPRIM
| ID: wpr-358287
ABSTRACT
<p><b>OBJECTIVE</b>To study the clinicalpathologic features of intracranial multiple lesions.</p><p><b>METHODS</b>The clinical, radiologic and pathologic features of intracranial multiple lesions in 62 cases during the period from 2005 to 2009 in Xuanwu Hospital were retrospectively reviewed.</p><p><b>RESULTS</b>There were 32 males and 30 females in 62 cases. The mean age of seize onset and duration of disease were 37.4-year-old and 11.6 months, respectively. The lesions could affect cerebral hemisphere, basal ganglia, brain stem, cerebellum and other parts, most lesions were located above the tentorium. Pathological diagnosis as follows 13 patients with glioma; metastatic tumors in 13 cases; 12 cases of central nervous system infection; immune-mediated inflammatory demyelinating disease in 8 cases; 5 cases of primary lymphoma of central nervous system; primary angiitis of the central nervous system 3 cases; mitochondrial encephalopathy 2 cases; vein thrombosis in 2 cases; Rosai-Dorfman disease in 2 cases; 2 case of radiation encephalopathy. Among them, mitochondrial encephalopathy and vein thrombosis lesions located in the cortex; metastatic tumor and blood-borne infection mainly involving junction of grey and white matter; glioma, radiation encephalopathy and demyelinating disease include white matter lesions; vascular inflammation showed cortical and subcortical white matter lesions.</p><p><b>CONCLUSIONS</b>A variety of tumor and non-neoplastic diseases can be expressed in intracranial multiple lesions, which gliomas, metastatic tumor and central nervous system infections are more common. In order to improve the diagnosis of intracranial multiple lesions, active work in the brian biopsy, study the clinical, imaging and pathological findings must be closely.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Cirurgia Geral
/
Neoplasias Encefálicas
/
Imageamento por Ressonância Magnética
/
Histiocitose Sinusal
/
Estudos Retrospectivos
/
Linfoma Difuso de Grandes Células B
/
Doenças Desmielinizantes
/
Toxoplasmose Cerebral
/
Neoplasias Neuroepiteliomatosas
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
Limite:
Adolescente
/
Adulto
/
Idoso
/
Criança
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Pathology
Ano de publicação:
2011
Tipo de documento:
Artigo
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