Therapeutic options and prognosis of synchronous multiple primary colorectal carcinomas / 中华肿瘤杂志
Chinese Journal of Oncology
;
(12): 435-437, 2005.
Artigo
em Chinês
| WPRIM
| ID: wpr-358610
ABSTRACT
<p><b>OBJECTIVE</b>To investigate the therapeutic principles and prognosis of synchronous primary colorectal carcinomas (SCC).</p><p><b>METHODS</b>The data of 66 SCC patients surgically treated from 1984 to 2003 were retrospectively reviewed.</p><p><b>RESULTS</b>The synchronous primary colorectal carcinomas were diagnosed and resected simultaneously in 65 patients except one that was misdiagnosed. Thirty patients underwent combined resection, 35 patients segmental resection. Sixty-two patients received radical resection, while three patients had palliative resection due to hepatic metastasis. The overall postoperative 3-, 5-, 10-year survival rates were 70.3%, 60.0%, 40.6%, respectively. In the patients who had simultaneous radical resection, the 3-, 5-, 10-year survival rates were 76.0%, 65.9%, 46.4% respectively.</p><p><b>CONCLUSION</b>The extent of resection should be individually determined by the lesion location, extent and distance between the lesions, as well as the patient's general condition. More extensive bowel resection, such as total or subtotal colectomy are suggested for those patients with hereditary nonpolyposis colorectal carcinoma syndrome in order to reduce or avoid the risk of metachronous colorectal carcinoma. The postoperative survival in patients with synchronous primary colorectal carcinoma is similar to those with solitary lesion.</p>
Texto completo:
DisponíveL
Índice:
WPRIM (Pacífico Ocidental)
Assunto principal:
Neoplasias Ovarianas
/
Patologia
/
Prognóstico
/
Neoplasias Gástricas
/
Cirurgia Geral
/
Neoplasias Colorretais
/
Neoplasias Colorretais Hereditárias sem Polipose
/
Taxa de Sobrevida
/
Mortalidade
/
Genética
Tipo de estudo:
Estudo prognóstico
Limite:
Adulto
/
Idoso
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Chinese Journal of Oncology
Ano de publicação:
2005
Tipo de documento:
Artigo
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